Features of mir-466-3p binding sites in mRNA genes with different functions

  • R. Niyazova Al-Farabi Kazakh National University, Almaty, Kazakhstan
  • Sh. Atambayeva
  • A. Akimniyazova Al-Farabi Kazakh National University, Almaty, Kazakhstan
  • I. Pinsky Al-Farabi Kazakh National University, Almaty, Kazakhstan
  • A. Alybaeva Al-Farabi Kazakh National University, Almaty, Kazakhstan
  • B. Faye CIRAD, Montpellier, France
  • A. Ivashchenko Al-Farabi Kazakh National University, Almaty, Kazakhstan

Abstract

The importance of miRNA in cellular regulation is gaining momentum. We searched miRNA binding sites using the MirTarget program. We identified several miRNAs that have greater than 300 target genes in humans, with multiple binding sites per gene. We observed that miR-466-3p 1,463 binding sites with high affinity (with ΔG/ΔGm values greater than or equal to 90%).

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How to Cite
NIYAZOVA, R. et al. Features of mir-466-3p binding sites in mRNA genes with different functions. International Journal of Biology and Chemistry, [S.l.], v. 8, n. 2, p. 44-51, dec. 2015. ISSN 2409-370X. Available at: <http://ijbch.kaznu.kz/index.php/kaznu/article/view/189>. Date accessed: 11 dec. 2017.
Section
Biology

Keywords

binding; sites; genes