Phenolic profiles and brine shrimp cytotoxicity of the ethanolic extract from the aerial part of Crocus alatavicus L.

Authors

  • D. N. Satybaldiyeva Al Farabi Kazakh National University, Almaty
  • V. K. Mursaliyeva Institute of Plant Biology and Biotechnology, Almaty
  • R. Mammadov Pamukkale University
  • B. K. Zayadan Al Farabi Kazakh National University, Almaty

DOI:

https://doi.org/10.26577/2218-7979-2016-9-1-38-41

Keywords:

Crocusalatavicus, phenolic compound, cytotoxicity, brine shrimp, extract

Abstract

The aim of this study is to investigate the phenolic profiles and evaluate the brine shrimp cytotoxic activity of the ethanolic extract from the aerial part of C. alatavicus, an endemic species of Kazakhstan flora. Nine phenolic compounds were identified and quantified in the extract by high-performance liquid chromatography method. Preliminary cytotoxicity of the extract was determined by the brine shrimp (Artemiasalina) assay. The results reveal that the ethanolic extract from the aerial part of Crocus alatavicus exhibit a high cytotoxicity with LC50 15.71 μg/mL.

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Published

2016-06-30

How to Cite

Satybaldiyeva, D. N., V. K. Mursaliyeva, R. Mammadov, and B. K. Zayadan. 2016. “Phenolic Profiles and Brine Shrimp Cytotoxicity of the Ethanolic Extract from the Aerial Part of Crocus Alatavicus L”. International Journal of Biology and Chemistry 9 (1):38-41. https://doi.org/10.26577/2218-7979-2016-9-1-38-41.