Nanostructured Hydrogel Dressings On Base Of Crosslinked Polyvinylpyrrolidone For Biomedical Application

G. S. Irmukhametova, E. M. Shaikhutdinov, R. K. Rakhmetullayeva, B. B. Yermukhambetova, G. A. Mun, G. Temirkhanova

Abstract


Hydrogel dressings for biomedical application were obtained by -irradiation of poly-N-vinipirrolidon (PVP), agar-agar, polyethylene glycol and silver nitrate solution. Influence of irradiation doses (range from 25 kGy to 75 kGy), silver nitrate concentration and PVP concentration in initial monomer mixture on properties of obtained material were investigated. Presence and distribution of silver nanoparticles in obtained bandages is confirmed by optical microscopy and atomic force spectroscopy. Antimicrobial activity study in vitro showed antimicrobial activity, flexibility, high sorption capacity to water and biological fluids.

Keywords


hydrogel dressings; -irradiation; silver nanoparticles

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