Phenolic profiles and brine shrimp cytotoxicity of the ethanolic extract from the aerial part of Crocus alatavicus L.

  • D. N. Satybaldiyeva Al Farabi Kazakh National University, Almaty
  • V. K. Mursaliyeva Institute of Plant Biology and Biotechnology, Almaty
  • R. Mammadov Pamukkale University
  • B. K. Zayadan Al Farabi Kazakh National University, Almaty


The aim of this study is to investigate the phenolic profiles and evaluate the brine shrimp cytotoxic activity of the ethanolic extract from the aerial part of C. alatavicus, an endemic species of Kazakhstan flora. Nine phenolic compounds were identified and quantified in the extract by high-performance liquid chromatography method. Preliminary cytotoxicity of the extract was determined by the brine shrimp (Artemiasalina) assay. The results reveal that the ethanolic extract from the aerial part of Crocus alatavicus exhibit a high cytotoxicity with LC50 15.71 μg/mL.


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How to Cite
SATYBALDIYEVA, D. N. et al. Phenolic profiles and brine shrimp cytotoxicity of the ethanolic extract from the aerial part of Crocus alatavicus L.. International Journal of Biology and Chemistry, [S.l.], v. 9, n. 1, p. 38-41, jan. 2017. ISSN 2409-370X. Available at: <>. Date accessed: 27 june 2017.


Crocusalatavicus; phenolic compound; cytotoxicity; brine shrimp; extract