Study of the effect of cadmium, lead, zinc salts on the rat blood cells

Authors

  • G. K. Atanbaeva Al-Farabi Kazakh National University
  • S. T. Tuleuhanov Al-Farabi Kazakh National University
  • G. Daulet Al-Farabi Kazakh National University
  • M. Molsadykkyzy Al-Farabi Kazakh National University
  • S. O. Ossikbayeva Al-Farabi Kazakh National University
  • Z. S. Orynbayeva Drexel University College of Medicine

DOI:

https://doi.org/10.26577/2218-7979-2017-10-1-9-14
        58 42

Abstract

Changes were detected in the blood of rats caused by heavy metal compounds. The results show that the salts of heavy metals poisoning demonstrates in damage in the blood cells in the animal body and making weaker their immunity. As a result, various changes occur in animals. In addition, material was collected on immune depressive exposure to heavy metals in the body of rats 25, 50, 75, 100 times more compounds of zinc ions, lead and cadmium. Animal disorders were observed in the nervous system, including tearing, inflammation conjunctive sac and certain groups even with bleeding. Leukogram, which
was made by the blood of rats, showed that the poisoning caused by the impact of three types of heavy salts, has led to significant changes in the health and behavior of the animals. When increasing by 100 times more poisoning three compound salts in animal organisms have been found strong signs of poisoning,
finally, all experimental rats died within 5-6 days. It is important to note, animals poisoned by 75-100 times the maximum permissible concentration of heavy metal salts of the three compound salts have died. Leukogram of experimental rats showed that, in the blood of rats, poisoned by three salts, during
neutrophilia and lymphopenia, leukopenia was found. Neutrophils are characterized by granulated toxicity and gipersigmatich core.

Author Biography

Z. S. Orynbayeva, Drexel University College of Medicine

Department of Surgery

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How to Cite

Atanbaeva, G. K., S. T. Tuleuhanov, G. Daulet, M. Molsadykkyzy, S. O. Ossikbayeva, and Z. S. Orynbayeva. 2017. “Study of the Effect of Cadmium, Lead, Zinc Salts on the Rat Blood Cells”. International Journal of Biology and Chemistry 10 (1):9-14. https://doi.org/10.26577/2218-7979-2017-10-1-9-14.