Assessment of 13 Single Nucleotide Polymorphisms Loci for Identification in Forensic Sciences for Turkish Population

13 SNP Loci Identification for Turkish Population

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DOI:

https://doi.org/10.26577/ijbch.2021.v14.i1.05

Abstract

Single nucleotide polymorphisms (SNPs) are used for genetic identification in forensic science. In this study, 13 loci (rs876724, rs1357617, rs2046361, rs717302, rs917118, rs735155, rs901398, rs729172, rs740910, rs1493232, rs719366, rs1031825, rs722098) selected among 52 SNP plex’s whose importance in forensic sciences were determined before, were studied for the Turkish population. In addition to the discrimination power of the Turkish population as selected loci in this study, it was aimed to calculate the separation of powers showed in their Turkey geographic regions. For this purpose, blood samples taken from 50 volunteers' DNA samples were duplicated by polymerase chain reaction (PCR) and typed in a capillary electrophoresis device and genotype information was determined for 13 SNP loci. The data obtained showed parallelism with values published by the SNPforID Consortium. Obtained results proved the separation forces of the studied loci suitable for the Turkish population. The existence of Hardy-Weinberg Equation was tested for all studied loci and Hardy-Weinberg Equation was found in all loci except one loci (rs876724). Because of the fact that the number of samples is insufficient for geographical studies, no statistically significant difference was observed in other loci in the regional context except for the significant results obtained for rs729172 and rs740910 loci.

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Published

2021-07-02