Synthesis of new thermosensitive copolymers based on 2-hydroxyethylacrylate and 2-hydroxyethylmethacrylate and their interaction with surfactants
Keywords:
Thermo-sensitive copolymers, 2-hydroxyethylacrylate, 2-hydroxyethylmethacrylateAbstract
Thermo-sensitive linear and cross-linked copolymers based on 2-hydroxyethylacrylate and 2-hydroxyethylmethacrylate were synthesized and their physicochemical properties were investigated. It was found that copolymer solutions have LKST and copolymer hydrogels of certain composition undergoes sharp collapse at temperature increase. The interaction of copolymers with surfactants was studied. It was shown that swelling behavior of copolymers in surfactants aqueous solutions depend on several factors: copolymer composition, surfactant concentration. The reason for the observed phenomenon is discussed. Treatment of some hydrogels in surfactant solutions resulted in great enhancing of collapse amplitude and its sharpening.References
[2] A.S. Hoffman et al, J.Biomed. Mater. Res. 2000, 52, 577-586.
[3] T. Tanaka, Sci.Am. 1981, 244, 123.
[4] T. Tanaka, Phys. Rev.Lett. 1978, 40, 820.
[5] N.A. Peppas, CRC Press, Boca Raton, FL, 1987.
[6] Langer R., Drug delivery and targeting, Nature, 392, 5, 1998.
[7] Flory P.J., Principles of Polymer Chemistry, Cornell University Press, Ithaca, NY, 1953.
[8] Safrany A., Synthesis and characterization of superclean thermo-reversible copolymer hydrogels, Radiat. Phys. Chem., 55, p.121-126, 1999.
Downloads
How to Cite
Issue
Section
License
ааа












