Nanostructured Hydrogel Dressings On Base Of Crosslinked Polyvinylpyrrolidone For Biomedical Application

Authors

  • G. S. Irmukhametova Faculty of Chemistry and Chemical Technology, al-Farabi Kazakh National University
  • E. M. Shaikhutdinov Turysov Institute of geology and oil gas business, Satpayev Kazakh National Technical University
  • R. K. Rakhmetullayeva Faculty of Chemistry and Chemical Technology, al-Farabi Kazakh National University
  • B. B. Yermukhambetova Faculty of Chemistry and Chemical Technology, al-Farabi Kazakh National University
  • G. A. Mun Faculty of Chemistry and Chemical Technology, al-Farabi Kazakh National University
  • G. Temirkhanova Faculty of Chemistry and Chemical Technology, al-Farabi Kazakh National University

Keywords:

hydrogel dressings, -irradiation, silver nanoparticles

Abstract

Hydrogel dressings for biomedical application were obtained by -irradiation of poly-N-vinipirrolidon (PVP), agar-agar, polyethylene glycol and silver nitrate solution. Influence of irradiation doses (range from 25 kGy to 75 kGy), silver nitrate concentration and PVP concentration in initial monomer mixture on properties of obtained material were investigated. Presence and distribution of silver nanoparticles in obtained bandages is confirmed by optical microscopy and atomic force spectroscopy. Antimicrobial activity study in vitro showed antimicrobial activity, flexibility, high sorption capacity to water and biological fluids.

References

1. Biomedical Applications of Hydrogels Handbook, Offenbrite R.M. (Editor-in-Chief), Park K. and Okano T. (Editors), Springer, 2010. - P.423.
2. R. Yoshida, T. Okano Stimuli-Responsive Hydrogels and Their Application to Functional Materials // In the Book: Biomedical Applications of Hydrogels Handbook, Offenbrite R.M. (Editor-in-Chief), Park K. and Okano T. (Editors), Springer, 2010. - Part 1. - P. 19 -44.
3. T. Miyata Biomolecule-Responsive Hydrogels, in: Biomedical Applications of Hydrogels Handbook, Offenbrite R.M. (Editor-in-Chief), Park K. and Okano T. (Editors), Springer, 2010. - Part 1. - P. 65-86.
4. M. Oishi, Y. Nagasaki Stimuli-Responsive PEGylated Nanogels for Smart Nanomedicine, in: Biomedical Applications of Hydrogels Handbook, Offenbrite R.M. (Editor-in-Chief), Park K. and Okano T. (Editors), Springer, 2010. - Part 1. - P. 87-120.
5. N.A. Peppas Physiologically Responsive Hydrogels // J. Bioact. Compat. Polym. – 1991. -Vol.6. - P. 241-246.

Published

2013-06-20

How to Cite

Irmukhametova, G. S., E. M. Shaikhutdinov, R. K. Rakhmetullayeva, B. B. Yermukhambetova, G. A. Mun, and G. Temirkhanova. 2013. “Nanostructured Hydrogel Dressings On Base Of Crosslinked Polyvinylpyrrolidone For Biomedical Application”. International Journal of Biology and Chemistry 5 (1):76-80. https://ijbch.kaznu.kz/index.php/kaznu/article/view/84.

Issue

Vol. 5 No. 1 (2013): International Journal of Biology and Chemistry

Section

Chemistry

License

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